Table 2.

Comparison of the accuracy of the ‘a priori’ and of the ‘updated’ algorithms for attribution of the first neuropsychiatric events in the three cohorts

Cohort	No of pts	A priori (original) algorithm		Updated algorithm
		AUC	(95% CI)	AUC	(95% CI)	p Value*
Cohort 1: Training 9	225	0.845	0.797 to 0.892	0.857	0.811 to 0.904	0.03
Cohort 2: Italian validating9	209	0.818	0.759 to 0.876	0.818	0.759 to 0.876	1.0
Cohort 3: International9	243	0.893	0.849 to 0.936	0.892	0.847 to 0.937	0.9
p Value†		0.10		0.13

AUC, area under curve.

*Intracohorts comparison.

†Intercohorts comparison.