Table 3.

Sensitivity, specificity, PPV and NPV for each defined cut-point derived from the application of the attribution algorithm (using ‘a priori’ coefficients) to the first NP event observed in the international cohort

Cut-point	Sensitivity (%)	Specificity (%)	Correctly classified (%)	LR+	LR−	PPV (%)	NPV (%)
(≥0)	100.0	0.0	40.7	1		40.7
(≥1)	100.0	1.4	41.6	1.0141	0	41.1	100.0
(≥2)	99.0	6.2	44.0	1.0559	0.1616	42.1	90.0
(≥3)	99.0	16.7	50.2	1.1879	0.0606	45.0	96.0
(≥4)	96.0	31.9	58.0	1.41	0.1265	49.2	92.0
(≥5)	92.9	48.6	66.7	1.8084	0.1455	55.4	90.9
(≥6)	91.9	71.5	79.8	3.2284	0.113	68.9	92.8
(≥7)	87.9	82.6	84.8	5.0618	0.1467	77.7	90.8
(≥8)	69.7	91.0	82.3	7.7203	0.3331	84.1	81.4
(≥9)	47.5	97.2	76.9	17.0909	0.5403	92.1	72.9
(≥10)	19.2	99.3	66.7	27.6364	0.8137	95.0	64.1
(>10)	0.0	100.0	59.3	1			59.3

LR, likelihood ratio; NPV, negative predictive value; NP, neuropsychiatric; PPV, positive predictive value.