Figure 1.

Schematic illustration of the model. The bacterial cell is modelled as a well-mixed vessel, containing ribosomes (dark blue) which may be free or bound by antibiotic. Antibiotic molecules (black circles) can be transported into or out of the cell (pink arrow) and can bind to or dissociate from ribosomes (orange arrow). The model also includes cell growth (green) and ribosome synthesis (light blue), both of which are coupled to the state of the cell (these couplings are illustrated by the grey arrows).