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. 2017 Dec 14;15(12):e2003217. doi: 10.1371/journal.pbio.2003217

Table 2. Assignment of nonhuman primates to blocks of 3-character categories.

ICD-10 classification Cynomolgus monkeys Rhesus monkeys Marmosets and tamarins Total Percentage of target group ‘patients’
Chapter Number Blocks of 3-character category1
Certain infectious and parasitic diseases I B15–B19 46 - - 46 7
B20–B24 - 32 - 32
B95–B98 - 78 - 78
Neoplasms II C15–C26 130 - - 130 29
C60–C63 30 - - 30
C69–C72 78 - - 78
C76–C80 126 9 - 135
C81–C96 152 - - 152
multiple 100 - - 100
Endocrine, nutritional, and metabolic disorders IV E65–E68 15 - - 15 1
Mental and behavioural disorders V F00–F09 54 - - 54 4
F20–F29 - 6 - 6
F80–F89 - - 21 21
F00–F992 2 - - 2
Diseases of the nervous system VI G10–G14 234 - - 234 17
G20–G26 6 - 18 24
G30–G32 61 - - 61
G35–G37 40 - - 40
multiple - - 6 6
Diseases of the eye and adnexa VII H40–H42 10 - - 10 <1
Diseases of the circulatory system IX I20–I25 21 - - 21 2
I30–I52 - 25 - 25
Diseases of the respiratory system X J40–J47 - - 50 50 2
Diseases of the musculoskeletal system and connective tissue XIII M00–M03 66 - 10 76 13
M05–M14 96 - - 96
M30–M36 70 - - 70
multiple 36 - - 36
Diseases of the genitourinary system XIV N30–N39 43 - - 43 2
Multiple chapters 457 32 15 504 23
Total 1,873 120 182 2,175

All nonhuman primates of NTSs submitted in 2015 (n = 4,024) were allocated to ICD-10 chapters and blocks-of-3-characters categories. Data are presented as the total number of animals and, with respect to the ICD-10 chapters, as the percentages of all animals assigned to the target group ‘patients’. Deviations from 100% are due to mathematical rounding.

1B15–B19, Viral hepatitis; B20–B24, Human immunodeficiency virus (HIV) disease; B95–B98, Bacterial, viral and other infectious agents; C15–C26, M.n. of digestive organs; C60–C63, M.n. of male genital organs; C69–C72, M.n. of eye, brain and other parts central nervous system; C76–C80, M.n., secondary and ill-defined; C81–C96, M.n., stated or presumed to be primary, of lymphoid, haematopoietic and related tissue; E65–E68, Obesity and other hyperalimentation; F00–-F09, Organic, including symptomatic, mental disorders; F20–F29, Schizophrenia, schizotypal and delusional disorders; F80–F89, Disorders of psychological development; F00–F99, Mental and behavioural disorders2; G10–G14, Systemic atrophies primarily affecting the central nervous system; G20–G26, Extrapyramidal and movement disorders; G30–G32, Other degenerative diseases of the nervous system; G35–G37, Demyelinating diseases of the central nervous system; H40–H42, Glaucoma; I20–I25, Ischemic heart diseases; I30–I52, Other forms of heart disease; J40–J47, Chronic lower respiratory diseases; M00–M03, Infectious arthropathies; M05–M14, Inflammatory polyarthropathies; M30–M36, Systemic connective tissue disorders; N30–N39, Other diseases of urinary system.

2Only allocation to the ICD-10 chapter was possible.

Abbreviations: M.n., Malignant neoplasms; NTS, nontechnical summary.