Skip to main content
. 2017 Dec 14;12(12):e0189478. doi: 10.1371/journal.pone.0189478

Table 4. Central composite design experiments and experimental results.

Runs Independent variables
in coded form
Independent variables
in their natural form
Tgel value (°C)
407
(%)
188
(%)
HPMC (%) 407
(%)
188
(%)
HPMC
(%)
Predicted Actual
1 1.0 1.0 -1.0 22.8 6.6 0.3 30.4 29.4±0.1
2 -1.0 1.0 -1.0 19.2 6.6 0.3 41.8 41.9±0.3
3 0.0 0.0 -1.6818 21.0 4.5 0.1 31.9 31.8±0.2
4 1.0 -1.0 1.0 22.8 2.4 0.8 24.4 24.3±0.3
5 0.0 0.0 1.6818 21.0 4.5 1.0 30.4 30.5±0.2
6 1.0 -1.0 -1.0 22.8 2.4 0.3 25.4 25.2±0.1
7 1.0 1.0 1.0 22.8 6.6 0.8 29.9 28.6±0.3
8 -1.6818 0.0 0.0 18.0 4.5 0.6 41.5 40.0±0.2
9 -1.0 1.0 1.0 19.2 6.6 0.8 41.0 41.1±0.3
10 -1.0 -1.0 1.0 19.2 2.4 0.8 33.0 34.0±0.2
11 1.6818 0.0 0.0 24.0 4.5 0.6 24.7 26.2±0.1
12 0.0 1.6818 0.0 21.0 8.0 0.6 38.5 39.7±0.3
13 -1.0 -1.0 -1.0 19.2 2.4 0.3 34.2 35.4±0.2
14 0.0 -1.6818 0.0 21.0 1.0 0.6 27.5 26.3±0.1
15~20 0.0 0.0 0.0 21.0 4.5 0.6 30.6 30.6±0.1