Table 1. Feature comparison of pSSAlib with other exact SSA simulation packages.

(SBML: supports SBML model input, pSSA: provides partial-propensity SSAs, Diffusion: provides spatiotemporal stochastic reaction-diffusion, Delays: provides chemical reactions with time delays, Events: provides event triggers).

Software package	SBML	pSSA	Diffusion	Delays	Events
pSSAlib 2.0.0	☑	☑	Cartesian NSM	☑	□
libRoadRunner 1.3.0 [29]	☑	□	□	□	☑
StochKit 2.0.13 [28]	☑	□	□	□	☑
Cain 1.10 [27]	☑	□	□	□	☑
URDME 1.3 [30]	□	□	Tetrahedral NSM	□	□