Table 3.

Predictors of Major Bleeding

Significant Characteristics	Odds Ratio	95% Confidence Interval		P-Value
Perioperative aspirin continuation	3.576	1.077	11.874	0.0375
Postprocedure day 0 to 10a	3.505	1.797	6.867	0.0002
High bleeding risk procedureb	2.861	1.390	5.890	0.0043
History of renal disease	2.853	1.351	6.027	0.0060
Dalteparin bridge therapy	2.443	1.240	4.813	0.0098
INR > 3 (per unit)	2.115	1.466	3.052	<.0001
Nonsignificant Characteristics
History of liver disease	1.743	0.387	7.852	0.4691
History of heart failure	1.538	0.806	2.935	0.1915
History of gastrointestinal bleeding	1.449	0.466	4.509	0.5221
History of stroke or TIA	1.444	0.676	3.087	0.3425
Age > 65 years	1.353	0.593	3.089	0.4728
History of hypertension	1.320	0.465	3.752	0.6019
History of diabetes	1.063	0.560	2.019	0.8513
Female sexc	0.946	0.460	1.946	0.8805

C-index = 0.655

^a– Referent group is days 11 through 37;

^b– Referent group is low bleeding risk procedures;

^c–Referent group is male sex

INR - international normalized ratio; TIA – transient ischemic attack