Table 1.
A list of genes transcriptionally modulated during GSC differentiation.
| Up-regulated genes |
Down-regulated genes |
||||||||
|---|---|---|---|---|---|---|---|---|---|
| Transcript Cluster ID | Fly Gene Symbol | Human Ortholog | Fold Change | FDR p-value | Transcript Cluster ID | Fly Gene Symbol | Human Ortholog | Fold Change | FDR p-value |
| 18197227 | CG14369 | N/A | 14.03 | 0.004053 | 18143346 | Ref2 | ALYREF | −1.5 | 0.013804 |
| 18200889 | Gr93d | N/A | 9.34 | 0.019055 | 18198373 | CG17186 | N/A | −1.5 | 0.014708 |
| 18164680 | CG43110 | GZMH | 7.17 | 0.013804 | 18133084 | CG5440 | UBE2E3 | −1.51 | 0.030002 |
| 18199988 | CG10000 | GALNT14 | 6.17 | 0.008274 | 18194131 | wts | LATS2 | −1.51 | 0.02603 |
| 18145258 | CG33307 | N/A | 5.99 | 0.0268 | 18188101 | sosie; CR45216 | N/A | −1.53 | 0.016607 |
| 18141312 | CG3528 | C4orf22 | 5.62 | 0.004053 | 18171734 | CG33217 | PELP1 | −1.54 | 0.023726 |
| 18162277 | CG2736 | SCARB2 | 5.57 | 0.006617 | 18188937 | CG11897 | ABCC4 | −1.54 | 0.045327 |
| 18138530 | CG43402 | N/A | 4.75 | 0.010525 | 18162274 | Phk-3 | N/A | −1.55 | 0.033 |
| 18156218 | gsb-n | PAX3 | 4.66 | 0.02644 | 18194371 | mia | TAF6L | −1.56 | 0.028082 |
| 18134734 | dpr19 | USH2A | 4.09 | 0.008924 | 18169211 | Tgi | VGLL4 | −1.56 | 0.004262 |
| 18144843 | CG31777 | N/A | 4.04 | 0.047532 | 18145722 | del | N/A | −1.57 | 0.042923 |
| 18185346 | CG18473 | PTER | 4.02 | 0.023605 | 18189333 | CG11333 | ISOC1 | −1.6 | 0.020327 |
| 18136286 | Gr32a | GZMH | 3.85 | 0.006331 | 18145631 | CG34367 | SHOX2 | −1.6 | 0.020466 |
| 18151208 | CG10764 | N/A | 3.85 | 0.023075 | 18142936 | CG5676 | FUNDC1 | −1.61 | 0.038272 |
| 18180564 | CG34025 | N/A | 3.31 | 0.030731 | 18151843 | maf-S | MAFK | −1.62 | 0.032486 |
| 18132093 | Acyp | ACYP2 | 3.23 | 0.049199 | 18146894 | a | PDZD2 | −1.62 | 0.045041 |
| 18197785 | CG14905 | CCDC63 | 3.09 | 0.042576 | 18155416 | mi | N/A | −1.62 | 0.02644 |
| 18141034 | CG11912 | PRTN3 | 2.92 | 0.020284 | 18133793 | CG18269 | MCMBP | −1.63 | 0.049199 |
| 18136753 | CG31776 | GALNTL6 | 2.83 | 0.01447 | 18134015 | CG3430 | N/A | −1.63 | 0.047739 |
| 18157091 | imd | PIDD1 | 2.72 | 0.004053 | 18135993 | DCTN5-p25 | DCTN5 | −1.63 | 0.030878 |
| 18139932 | cutlet | CHTF18 | 2.68 | 0.027276 | 18161200 | Or56a | N/A | −1.64 | 0.046053 |
| 18163569 | sprt | PARD3B | 2.66 | 0.048525 | 18151370 | CG14500 | N/A | −1.64 | 0.031712 |
| 18177597 | CG10361 | GCAT | 2.61 | 0.018769 | 18165004 | CG43668 | N/A | −1.65 | 0.029659 |
| 18135200 | CG16820 | N/A | 2.61 | 0.047532 | 18202690 | CG42487; CG4884 | C6orf203 | −1.65 | 0.034006 |
| 18154275 | Idgf5 | CHIT1 | 2.6 | 0.027711 | 18187489 | Fadd | PIDD1 | −1.68 | 0.034006 |
| 18143767 | Cyp310a1 | TBXAS1 | 2.55 | 0.004184 | 18168671 | CG3335 | RBM19 | −1.69 | 0.028633 |
| 18135886 | CG1421 | N/A | 2.54 | 0.004262 | 18173465 | Mocs1 | MOCS1 | −1.7 | 0.046053 |
| 18156154 | Cyp6a2 | TBXAS1 | 2.47 | 0.016296 | 18202203 | Nlg3 | NLGN4Y | −1.73 | 0.045041 |
| 18141305 | CG18641 | LIPI | 2.45 | 0.022122 | 18183067 | GstD5 | VARS | −1.75 | 0.028009 |
| 18168480 | CG13309 | N/A | 2.45 | 0.01418 | 18151405 | GstE1 | GSTT2B | −1.75 | 0.018895 |
| 18201360 | CG31174 | DCTN3 | 2.36 | 0.006981 | 18178062 | CG18649 | N/A | −1.77 | 0.019055 |
| 18152278 | CG13527 | N/A | 2.35 | 0.028082 | 18137896 | gkt | TDP1 | −1.83 | 0.020721 |
| 18165049 | CG43742 | N/A | 2.35 | 0.046053 | 18191472 | tal-AA; tal-1A; tal-2A; tal-3A | N/A | −1.84 | 0.0268 |
| 18188796 | CG1894 | KAT8 | 2.32 | 0.04604 | 18161799 | RpL37b | RPL37 | −1.91 | 0.044144 |
| 18197860 | CG17477 | KLK14 | 2.24 | 0.044589 | 18179059 | CG7298 | N/A | −1.97 | 0.034066 |
| 18136253 | Tep3 | CD109 | 2.23 | 0.015042 | 18195064 | Aats-met-m | MARS2 | −2.04 | 0.006981 |
| 18202255 | CG34283 | GTSF1L | 2.2 | 0.01418 | 18132382 | CG17834 | N/A | −2.05 | 0.034006 |
| 18191104 | CG34436 | N/A | 2.16 | 0.015331 | 18199863 | CG5402 | N/A | −2.07 | 0.033 |
| 18131563 | Ance | ACE | 2.15 | 0.02719 | 18139318 | prd | PAX3 | −2.11 | 0.02995 |
| 18130728 | salr | SALL4 | 2.11 | 0.043396 | 18141809 | Vps52 | VPS52 | −2.15 | 0.006981 |
| 18179578 | CG13053 | N/A | 2.11 | 0.041534 | 18138505 | Phae1 | PRSS53 | −2.16 | 0.023724 |
| 18141944 | CG9107 | RRP7A | 2.09 | 0.023266 | 18193273 | Blm | BLM | −2.17 | 0.047191 |
| 18144661 | CG31639 | UCHL5 | 2.08 | 0.013804 | 18187075 | CG16727 | SLC22A24 | −2.18 | 0.044165 |
| 18195851 | CG11286 | LAPTM5 | 2.07 | 0.006981 | 18133474 | CG2772 | LIPN | −2.3 | 0.0268 |
| 18180053 | CG32232 | TUBGCP5 | 2.04 | 0.018899 | 18190914 | CG34278 | N/A | −2.32 | 0.033063 |
| 18201456 | CG31244 | TACO1 | 2.04 | 0.026546 | 18160388 | CG8195 | SLC35F5 | −2.41 | 0.027265 |
| 18186923 | CG7694 | RNF181 | 2.03 | 0.0268 | 18185768 | CG14715 | FKBP2 | −2.51 | 0.034006 |
| 18201815 | CG32945 | N/A | 2.01 | 0.010525 | 18199680 | TwdlP | N/A | −2.51 | 0.015833 |
| 18200489 | CG15563 | N/A | 1.97 | 0.025277 | 18206397 | Cp7Fb | N/A | −2.62 | 0.015445 |
| 18146064 | CG42399 | FAM179B | 1.97 | 0.02644 | 18152912 | CG3829 | SCARB2 | −2.74 | 0.01418 |
| 18185352 | CG8129 | SRR | 1.95 | 0.042771 | 18178266 | CG13047 | N/A | −3.53 | 0.043603 |
| 18136832 | Qtzl | SCLY | 1.92 | 0.047532 | 18186763 | CG17283 | REN | −4.83 | 0.033 |
| 18167562 | CG12017 | N/A | 1.92 | 0.006981 | 18170763 | CG11458 | N/A | −5.23 | 0.019055 |
| 18142751 | CG4438 | PDAP1 | 1.89 | 0.0268 | 18169512 | CG13445 | N/A | −6.13 | 0.015445 |
| 18175784 | CG2211 | JMJD6 | 1.88 | 0.027711 | 18169271 | CG8100 | N/A | −15.57 | 0.006981 |
| 18190415 | CG31465 | N/A | 1.87 | 0.004053 | 18171820 | CG33500 | N/A | −18.66 | 0.010997 |
| 18186284 | CG3259 | TRAF3IP1 | 1.86 | 0.01269 | |||||
| 18138632 | CG43707 | RHPN2 | 1.86 | 0.030878 | |||||
| 18136825 | ZnT33D | SLC30A3 | 1.85 | 0.017284 | |||||
| 18133131 | Der-1 | DERL1 | 1.85 | 0.004184 | |||||
| 18164674 | CG43108 | N/A | 1.84 | 0.046581 | |||||
| 18131918 | SA | STAG1 | 1.84 | 0.046053 | |||||
| 18131649 | Try29F | PRSS3 | 1.84 | 0.01418 | |||||
| 18204185 | CG32006 | FOXJ1 | 1.83 | 0.029567 | |||||
| 18143367 | CG17036 | SLC19A2 | 1.82 | 0.004625 | |||||
| 18183737 | Gcn2 | EIF2AK4 | 1.78 | 0.02644 | |||||
| 18158424 | CG14591 | TMEM164 | 1.75 | 0.02669 | |||||
| 18153402 | CG30056 | N/A | 1.67 | 0.025134 | |||||
| 18181298 | nbs | NBN | 1.65 | 0.049927 | |||||
| 18199613 | CG4960 | REEP5 | 1.64 | 0.041962 | |||||
| 18198659 | CG6475 | UGT2B10 | 1.63 | 0.038221 | |||||
| 18145247 | Muc30E | MPV17L2 | 1.62 | 0.041534 | |||||
| 18180076 | CG32263 | N/A | 1.62 | 0.045041 | |||||
| 18142588 | Ostgamma | TUSC3 | 1.61 | 0.015445 | |||||
| 18177436 | Ufd1-like | UFD1L | 1.61 | 0.018179 | |||||
| 18203120 | CG42778 | N/A | 1.61 | 0.043368 | |||||
| 18192979 | Dip-C | PEPD | 1.6 | 0.046053 | |||||
| 18160269 | Adgf-E | CECR1 | 1.58 | 0.020284 | |||||
| 18138273 | CG43050 | MAIP1 | 1.58 | 0.018766 | |||||
| 18152420 | CG9863 | N/A | 1.58 | 0.046581 | |||||
| 18134839 | CG6094 | MRPL58 | 1.57 | 0.028082 | |||||
| 18164795 | CG43326; CG43325 | N/A | 1.57 | 0.03253 | |||||
| 18149666 | Cyp4p3 | CYP4Z1 | 1.57 | 0.010525 | |||||
| 18177352 | CG6674 | TSSC4 | 1.56 | 0.046581 | |||||
| 18161537 | lox2 | LOXL3 | 1.56 | 0.026405 | |||||
| 18185958 | Gnmt | GNMT | 1.55 | 0.0365 | |||||
| 18134385 | CG13090 | MOCS3 | 1.55 | 0.027298 | |||||
| 18175967 | CG5687 | SLC5A6 | 1.55 | 0.015445 | |||||
| 18199611 | CG4956 | ZDHHC24 | 1.54 | 0.04802 | |||||
| 18153798 | Mal-A6 | SLC3A1 | 1.53 | 0.010525 | |||||
| 18196850 | CG3313 | DCAF12 | 1.52 | 0.010997 | |||||
| 18153174 | Obp56i | N/A | 1.51 | 0.044165 | |||||
| 18163701 | CG34216 | N/A | 1.51 | 0.014708 | |||||
| 18142869 | CG5846 | SMOX | 1.5 | 0.046053 | |||||
| 18177135 | CG5653 | RFXANK | 1.5 | 0.020284 | |||||
| 18162351 | CG16926 | N/A | 1.5 | 0.048525 | |||||