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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Am J Surg Pathol. 2018 Jan;42(1):84–94. doi: 10.1097/PAS.0000000000000920

Table 6.

Statistical Analysis of Recurrent Smooth Muscle Tumors Among Patients with Clinical Follow Up.

Variable Tumors Any Recurrence 2 Year Recurrence-free Survival % (95% CI) p-value
Site 0.4883
Vagina 49 9 81.9% (69.6%, 94.2%)
Vulva 14 3 92.9% (79.4%, 100%)
Tumor Size ≥ 5 cm 0002
No 45 3 94.2% (86%, 100%)
Yes 18 9 60.3% (34.7%, 86%)
Degree of Atypia <0001
Mild to Moderate 46 1 96.4% (89.6%, 100%)
Moderate to Severe 17 11 53.4% (27.1%, 79.8%)
Mitotic Index ≥ 10/10 HPFs <0001
No 51 3 97.4% (92.5%, 100%)
Yes 12 9 26.7% (0%, 57.2%)
Atypical Mitotic Figures <0001
Mitotic Index of Zero 36 0 100%*
No 13 1 100%*
Yes 14 11 36.3% (8.8%, 63.8%)
Tumor Cell Necrosis <0001
No 52 2 97.5% (92.7%, 100%)
Yes 11 10 31.2% (2.2%, 60.1%)
Ischemic Necrosis <0001
No 49 3 94.5% (86.7%, 100%)
Yes 14 9 52.6% (24.6%, 80.6%)
Pattern of Infiltration 0053
Circumscribed 29 2 85.7% (67.4%, 100%)
Infiltrative 16 8 66.1% (41.7%, 90.5%)
Unknown 18 2 94.4% (83.9%, 100%)
Pattern of Infiltration (Unknown Excluded) 0042
Circumscribed 29 2 85.7% (67.4%, 100%)
Infiltrative 16 8 66.1% (41.7%, 90.5%)
*

Confidence interval non-estimable due to sparse data

HPFs (high power fields)