(A) Fungal colony forming units (CFUs) in the feces with or without supplementing fluconazole (FLUC) to specific-pathogen free mice previously administered C. albicans (CA) and maintained on drinking water supplemented with an antibiotic cocktail (ABX) containing ampicillin, gentamicin, metronidazole, neomycin, and vancomycin.
(B) Percent survival after DSS supplementation in the drinking water (for six days) for mice described in panel (A).
(C) Percent survival after influenza A PR8-OVA (Flu A) intranasal infection (6 × 104 PFUs) for mice described in panel (A).
*P < 0.05, **P < 0.001, by Log-rank (Mantel-Cox) test. Data are representative of at least two independent experiments each with similar results. Bars, mean ± s.e.m. L.o.D., limit of detection.