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. Author manuscript; available in PMC: 2018 Jun 6.
Published in final edited form as: Nature. 2017 Dec 6;552(7684):244–247. doi: 10.1038/nature25019

Figure 1. MMb mice have more severe colitis than HMb mice.

Figure 1

a and b. Weight change (a) and survival (b) of GF (red; n=12 mice), MMb (blue; n=10 mice), HMb (green; n=12 mice), and SPF (yellow; n=12 mice) mice subjected to DSS-induced colitis. In panel a, mean ± SEM values are depicted. c. Histologic assessment of disease severity in the colon at days 5 (n=6 mice per group) and 10 (n=3 mice per group) after induction of colitis in MMb (blue), HMb (green), and SPF (yellow) mice. Bars depict mean ± sem values. NS, not significant; *, p<0.05; **, p<0.01; ****, p<0.0001 by two-tailed t test (a, c) or log-rank test (b). Panels a and b include data pooled from 3 experiments, and panel c includes data pooled from 2 experiments.