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. Author manuscript; available in PMC: 2018 Jun 6.
Published in final edited form as: Nature. 2017 Dec 6;552(7684):244–247. doi: 10.1038/nature25019

Figure 3. Clostridium immunis protects MMb mice from colitis.

Figure 3

a. Relative abundance of bacterial families present in HMb feces before (left) and after (right) culture. b. Survival of MMb mice orally receiving MMb cx (blue; n=9 mice) or HMb cx (green; n=9 mice) and subjected to DSS-induced colitis. Data are pooled from 2 independent experiments. c. Relative abundance of Lachnospiraceae in a subset of the mice depicted in panel b. The fecal microbiota was assessed before gavage with any material (MMb) or 1 week after gavage with MMb cx or HMb cx (n=9, 5, and 4 mice, respectively). The post-gavage samples represent day 0 of the DSS colitis experiment. Individual (dots) and mean (bars) values are shown. d. Survival of MMb mice orally receiving Clostridium innocuum (green; n=5 mice) or C. immunis (blue; n=5 mice) and subjected to DSS-induced colitis. Data are representative of 2 independent experiments. NS, not significant; *, p<0.05; **, p<0.01 by log-rank (b, d) or a two-tailed Mann-Whitney test (c).