Figure 2.
Margin determination in case 3 using handheld reflectance confocal microscopy with radial videomosaicking. A, Videomosaic obtained from a video acquired at the 1 o’clock position from the center to the periphery (Video 1). Lentigo maligna extension was based on: 2.5 mm paper ring rim width (asterisk), and the field of view (FOV) of the handheld reflectance confocal microscope is 1mm, which equals 1000 pixels (panel B). B, Single FOV at the edge showing single dendritic cells continuing from the trailing edge of a lentigo maligna at the 1 o’clock position. C, Digital overlap of videomosaics depicting 3 radial videomosaics obtained in 3 different lesion quadrants. D, Videomosaic map digitally overlaid on clinical image to predict surgical margin based on 3mm histologic clearance.