Skip to main content
. 2015 Feb 9;2(1):15–26. doi: 10.1016/j.asmart.2014.11.001

Table 4.

Degradable biomaterials used in tissue-engineered ligament scaffolds.

Degradable polymers Representative investigators Publication year Advantages Defects
PLGA James et al115 2011 Controllable degradation rate; technologically mature Biologically inert; acidic degradation by-products
PGA Lin et al116 1999 Technologically mature Ready degradation; insufficient mechanical strength; hydrophobicity; adverse degradation product
PLLA Lu et al117 2005 Slow degradation rate; better cell affinity; technologically mature Hydrophobicity; adverse degradation product

PGA = poly(glycolic acid); PLGA = poly(lactic-co-glycolic acid); PLLA = poly(l-lactic acid).