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. 2017 Dec 13;38(1):e00302-17. doi: 10.1128/MCB.00302-17

FIG 5.

FIG 5

Cell-type-specific essential genes. (A) Expression level as a function of protein interaction degree for essential genes unique to the NALM-6 screen (red) versus UE genes (blue). (B) Average interaction degree for proteins encoded by UE genes, LE genes in NALM-6, and NE genes. (C) Expression levels of UE genes, LE genes in NALM-6, and NE genes. (D) Interactions between UE, CE, LE, and NE proteins. Counts were normalized by number of genes and interactions per class. (E) mRNA expression in NALM-6 cells of essential genes either unique to one or more B-cell-derived cell lines or unique to an equivalent number of other cell lines. (F) Participation in the B-cell receptor (BCR) pathway of essential genes either unique to one or more B-cell-derived cell lines or unique to an equivalent number of other cell lines.