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. 2017 Dec 13;38(1):e00181-17. doi: 10.1128/MCB.00181-17

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FIG 5 — CREB silencing blocked the pCPT-cAMP-induced increase in the protein expression of mitochondrial respiratory chain complexes. (A and B) Representative immunoblots and corresponding graph of mitochondrial respiratory chain complex proteins in podocytes treated with ADR in the absence or presence of pCPT for the indicated periods. (C to F) Representative immunoblots and corresponding graph of mitochondrial respiratory chain complex proteins in podocytes treated with CREB siRNA or a negative-control siRNA. Each bar represents data obtained from five independent experiments. (G) The regions within the ND3 promoter were analyzed by ChIP-qPCR. (H) Enrichment of CREB at the ND3 promoter. *, P < 0.05 compared with the control group; **, P < 0.05 compared with the ADR group; ***, P < 0.05 compared with the ADR-plus-pCPT-plus-ng group.