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. 2017 Dec 14;92(1):e01368-17. doi: 10.1128/JVI.01368-17

TABLE 2.

Incubation and survival times of Prnp+/0 and Tg(PrPΔOR-3608)/Prnp0/0 mice inoculated with BSE prions

Recipient mice PrP expression (fold)a No. of diseased mice/total Incubation time (days)b Survival time (days)c P valued
Prnp+/0 0.5 13/13 274 ± 6 290 ± 10 <0.0001
Tg(PrPΔOR-3608)/Prnp0/0 0.5 12/12 335 ± 26 343 ± 27
a

Expression levels were compared to those of PrPC in WT mice using Western blotting (Fig. 1B).

b

Time to onset of disease (average ± SD).

c

Time to terminal stage of disease (average ± SD).

d

The P value indicates the significance of comparison of incubation and survival times between Tg(PrPΔOR)/Prnp0/0 and Prnp+/0 mice by log rank (Mantel-Cox) test.