TABLE 4.
Dilution of DHBV cccDNAa
| Parameter | FISH count |
% reduction | |||
|---|---|---|---|---|---|
| Total | min./max. | Avg | Median | ||
| Day 1 | 3,502 | 0/54 | 18 | 15 | 0 (2,819)* |
| Day 4 | 2,955 | 0/58 | 15 | 12 | 19 |
| Day 8 | 1,452 | 0/38 | 7 | 6 | 73 |
| Day 12 | 734 | 0/32 | 4 | 2 | 98 |
| Day 17 | 780 | 0/31 | 4 | 3 | 97 |
| Day 25 | 844 | 0/29 | 4 | 3 | 94 |
| Control 1 | 801 | 0/15 | 4 | 3 | 100 (683)** |
| Control 2 | 564 | 0/9 | 3 | 2 | |
a
The table shows a summary of FISH counts from the experiment described in the Fig. 4 legend. Total, total FISH count from 200 nuclei derived from Dstet5 cells harvested at the indicated days; min./max., minimum/maximum (range of FISH counts); Avg, average of FISH counts; Median, median of FISH counts; Control, FISH counts from cells maintained in doxycycline; % reduction, percentage of reduction of FISH counts; *, the value in parentheses corresponds to the total count minus the control (background) value; **, the value in parentheses corresponds to the background value = the average of the control 1 and control 2 values.