FIG 4.

Capped RNA leader size influences the frequency of realignment, but differences in capped RNA leader size cannot account for the different tendencies of RSV and RGSV to use the prime-and-realign mechanism. (A) Stacked graphs showing the percentages of each type of HS (Fig. 1C) that associates with capped RNA leaders of a particular size, from 9 to 17 nt (x axis) for NP/NCP of RSV/RGSV. (B) The total percentages of type 1-1, 1-2, and 1-3 HSs associated with capped RNA leaders of a particular size (x axis). (C) Size distributions of the capped RNA leaders of the NP and NCP mRNAs of RSV/RGSV. The y axis shows the percentage of capped RNA leaders with a particular size, from 9 to 18 nt. For each mRNA, sequences from the four data sets (Fig. 1B) were pooled for the calculation shown here.