Table 1.
Exclusion Criteria and Tests Performed | Craven et al |
Kazerouni et al [9] | Paramsothy et al [10] | Costello et al [11] | Tariq et al [12] |
---|---|---|---|---|---|
History/Examination | |||||
Between 18 and 65 years of age | X | X | X | X | X |
Any medications | X | X | X | X | |
Antibiotics, antifungals, or antivirals in the last 3 months | X | X | X | X | X |
Probiotics in the last 3 months | X | X | X | ||
Hospitalization in the last 3 months | X | X | |||
Travel to high-risk areas of infectious diarrhea in the last 3 months | X | X | X | X | X |
Acute diarrhea within the past 6 months | X | ||||
Tattoo or body piercing in the last 6 months | X | X | X | X | X |
Known HIV or viral hepatitis exposure in the last 12 months | X | X | X | X | X |
High-risk sexual behavior | X | X | X | X | X |
Illicit drug use | X | X | X | X | X |
Incarceration or a history of incarceration | X | X | X | X | |
Household members with active GI infection | X | X | |||
Chronic constipation | X | ||||
Any gastrointestinal disorder | X | X | X | X | X |
Overweight (BMI >25) | X | X | |||
Obese (BMI >30) | X | X | X | ||
Hypertension | X | X | X | X | |
Type 2 diabetes | X | X | X | X | |
Insulin sensitivity | X | X | X | X | |
Hyperlipidemia | X | X | X | X | X |
Atherosclerosis | X | X | X | ||
Malnutrition (BMI <18) | X | X | X | ||
Autoimmune disease | X | X | X | X | X |
Atopic disease | X | X | X | ||
Psychiatric history | X | X | X | X | |
Infection with HIV, syphilis, hepatitis B or C | X | X | X | X | X |
Malignancy | X | X | X | X | X |
Chronic pain syndromes, neurologic or neurodevelopmental disorders | X | X | X | X | |
History of major gastrointestinal surgery | X | X | X | ||
Any kind of liver disease | X | ||||
Alcoholic intake >10 g/day women and >20 g/ day men | X | ||||
Family history of colorectal carcinoma | X | X | X | X | |
Family history of diabetes | X | ||||
Family history of early onset coronary disease, gastrointestinal or liver disease | X | X | |||
Stool Tests | |||||
Ova, cysts, and parasites | X | X | X | X | X |
Microscopy and culture | X | X | X | X | X |
Rotavirus | X | X | X | ||
Norovirus | X | X | X | X | |
Adenovirus | X | X | X | ||
Clostridium difficile toxin | X | X | X | X | X |
Vancomycin-resistant Enterococcus screen | X | X | X | X | |
Carbapenem-resistant Enterobacteriaceae | X | X | |||
Extended spectrum β-lactamase-producing Enterobacteriaceae | X | X | |||
Fecal Giardia antigen | X | X | X | X | |
Fecal Cryptosporidium antigen | X | X | X | X | |
Isospora | X | ||||
Cyclospora | X | ||||
Microsporidia | X | X | X | ||
Blood Tests | |||||
Complete blood count | X | X | X | X | |
Electrolytes, urea, and creatinine | X | X | X | ||
Liver function tests | X | X | X | X | |
Erythrocyte sedimentation rate | X | X | |||
C-reactive protein | X | X | X | ||
Fasting lipids and blood sugar level | X | X | |||
Anti-TTG antibody for celiac disease | X | ||||
Antinuclear antibody | X | ||||
HIV type 1 and 2 | X | X | X | X | X |
Hepatitis A virus IgM | X | X | X | X | X |
Hepatitis B virus surface antigen, hepatitis B virus core antibody (IgM and IgG), hepatitis B virus surface antibody | X | X | X | X | X |
Hepatitis C virus antibody | X | X | X | X | X |
Human T-cell lymphotropic virus 1 and 2 | X | X | X | X | |
Epstein-Barr virus IgM | X | X | |||
Cytomegalovirus IgM | X | X | |||
Strongyloides stercoralis, Entamoeba histolytica, Helicobacter pylori serology | X | X | X | ||
H pylori | X | X | X | ||
Treponema pallidum screening cascade | X | X | X | ||
Listeria | X | ||||
Nasal Swab | |||||
Methicillin-resistant Staphylococcus aureus | X | X | |||
Urine Tests | |||||
Gonorrhea and chlamydia | X |
Abbreviations: BMI, body mass index; GI, gastrointestinal; HIV, human immunodeficiency virus; Ig, immunoglobulin; TTG, tissue transglutaminase.
aScreening procedures of Kazerouni et al [9] are based on the OpenBiome safety guidelines [13].