Table 1.
Baseline | 4 weeks | 12 weeks | ||||
---|---|---|---|---|---|---|
Number per square millimeter | Diameter (μm) | Number per square millimeter | Diameter (μm) | Number per square millimeter | Diameter (μm) | |
CAPN3-KO | ||||||
STO | 158 | 31.16 ± 0.4 | 647 | 23.1 ± 0.3**** | 633 | 24.1 ± 0.3**** |
FTG/O | 316 | 40.81 ± 0.4 | 240 | 28.8 ± 0.6 | 153 | 35.8 ± 0.9** |
All fibers | 474 | 37.92 ± 0.3 | 887 | 24.6 ± 0.3**** | 786 | 26.4 ± 0.3**** |
Wild Type | ||||||
STO | 132 | 36.92 ± 0.5 | 466 | 26.2 ± 0.4 | 321 | 29.9 ± 0.4 |
FTG/O | 230 | 45.35 ± 0.4 | 256 | 29.9 ± 0.6 | 183 | 39.6 ± 0.7 |
All fibers | 362 | 42.27 ± 0.4 | 724 | 27.5 ± 0.3 | 504 | 33.3 ± 0.4 |
**** P < 0.0001 compared to same wild type parameter
**P < 0.01 compared to same wild type parameter