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Tibialis anterior muscle fiber size in CAPN3-KO mice following gene therapy
| CAPN3-KO | Untreated-TA | AAV.CAPN3.wt-treated TA | ||
|---|---|---|---|---|
| Number per square millimeter | Diameter (μm) |
Number per square millimeter | Diameter (μm) |
|
| STO | 355 | 32.72 ± 0.4 | 223 | 39.81 ± 0.6**** |
| FTG/O | 116 | 44.26 ± 0.9 | 99 | 50.40 ± 1.2**** |
| All fibers | 471 | 35.55 ± 0.4 | 322 | 43.08 ± 0.6**** |
**** P < 0.0001 compared to untreated parameter
