Table 2.
Univariate analysis of clinicopathologic variables in 100 patients with LSC (log-rank test)
| Variable | All cases | Mean survival(months) | Median survival(months) | P valuea |
|---|---|---|---|---|
| Age (years)b | 0.439 | |||
| ≤ 57 | 47 | 47.8 | 31.0 | |
| >57 | 53 | 55.4 | 18.0 | |
| Gender | 0.538 | |||
| Female | 13 | 37.4 | 27.0 | |
| Male | 87 | 55.2 | 25.0 | |
| Smoking | 0.078 | |||
| Yes | 76 | 59.4 | 43 | |
| No | 24 | 25.1 | 15.0 | |
| Tumor sizec | 0.032 | |||
| ≤ 4.5 cm | 59 | 65.8 | 48.0 | |
| >4.5 cm | 41 | 39.5 | 18.0 | |
| T stage | 0.033 | |||
| T1 And T2 | 56 | 63.2 | 48.0 | |
| T3 And T4 | 44 | 44.7 | 14.0 | |
| Lymph node | 0.000 | |||
| N0 | 52 | 74.7 | 68.0 | |
| N1,N2 And N3 | 48 | 31.4 | 14.0 | |
| M stage | 0.000 | |||
| M0 | 92 | 59.9 | 43.0 | |
| M1 | 8 | 12.1 | 8.0 | |
| Therapyd | 0.103 | |||
| Therapy1 | 76 | 62.2 | 48.0 | |
| Therapy2 | 19 | 28.9 | 21.0 | |
| Therapy3 | 5 | 19.0 | 24.0 | |
| Relapse | 0.713 | |||
| Yes | 30 | 36.4 | 24.0 | |
| No | 70 | 58.9 | 43.0 | |
| Clinical stage | 0.000 | |||
| I-II | 45 | 89.8 | NR | |
| III-IV | 55 | 19.5 | 11.0 | |
| p53R2 | 0.000 | |||
| Low expression | 42 | 84.8 | NR | |
| High expression | 58 | 34.7 | 12.0 |
aChi-square test
bMean age
cMean tumor size
dTherapy:Therapy1 is Pneumonectomy and lymphadenectomy, Therapy2 is Pneumonectomy;Therapy3 Pneumonectomy and radiotherapy and chemoradiotherapy