Hematoxylin and eosin (H&E) and immunohistochemical staining in 5 primary malignancies from the patient. a Invasive moderately differentiated adenocarcinoma in the endometrium. H&E staining. Magnification, ×100. b Invasive malignant melanoma of the left leg (Clark level II, Breslow 0.3 mm) at the pretibial region. Melan-A immunohistochemical staining. Magnification, ×400. c, d Invasive moderately differentiated adenocarcinoma in the colon ascendens. H&E staining. Magnification, ×5 (c), ×20 (d). e–f Spindle cell and pleomorphic cell sarcoma (grade 3 according to Trojani) in the left musculus biceps. H&E staining and α-SMA immunohistochemical staining. Magnification, ×200. g–h Invasive mucinous breast carcinoma (grade 2). McManus staining and estrogen receptor immunohistochemical staining. Magnification, ×40.