Table 1.
Reported cases of cholangiocarcinoma (CCA) associated with autoimmune hepatitis (AIH)
| Author | Year | Age, years | Sex | Serology | CCA type | CA-19 level | Time since diagnosis of AIH | Presence of cirrhosis at time of diagnosis | Follow-up since CCA diagnosis |
|---|---|---|---|---|---|---|---|---|---|
| Elfaki et al. [6] | 2008 | 55 | F | NA | Intrahepatic | 163 | 30 years | Possible cirrhosis | 7 months |
| Rial et al. [7] | 2010 | 64 | F | ANA +, AMA +, ASMA − |
Distal | NA | NA | Positive | NA |
| Izumi et al. [5] | 2010 | 81 | M | Negative | Intrahepatic | 99 | Acute | Negative | 28 months |
| Yoshizawa et al. [8] | 2012 | 60 | F | NA | NA | NA | 17 years | Negative | NA |
| Our case | 2017 | 57 | M | ANA −, ASMA −, AMA − |
Perihilar | 2.5 | 5 years | Negative | 1 year till present |
NA, not available. ANA, antinuclear antibody; ASMA, anti-smooth muscle antibody; AMA, antimitochondrial antibody; −, negative; +, present.