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. 2017 Sep 5;32(1):155–167. doi: 10.1096/fj.201700114RRR

Figure 2.

Figure 2.

Ca2+ signaling in acutely dissociated nasal turbinate ciliated cells in response to PAR-2 stimulation. A, B) PAR-2 agonist 2FLI [10 µM (black) or 1 µM (gray)]–activated [Ca2+]i elevation in ciliated cells. Traces in representative cells from 2 separate patients. A total of 14 cells from 3 separate patients were imaged at each concentration. C) 2FLI responses were blocked by preincubation with PLC inhibitor U73122 but not by inactive analog U73343 (n = 6 cells from 2 patients imaged for each condition). D) PAR-4 agonist AY-NH2 did not elevate [Ca2+]i (n = 6 cells from 2 patients). E) Bar graph showing peak results from experiments as in A–D. N.s., not significant. **P < 0.01.