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. 2017 Sep 6;32(1):183–194. doi: 10.1096/fj.201700166RR

Figure 2.

Figure 2.

Knockdown of adtrp1 expression disrupts the specification of primitive myelopoiesis during embryogenesis. A–H) Knockdown of adtrp1 expression did not affect the expression levels of gata1 (18 hpf, A, B; 24 hpf, C, D) and hbae1 (18 hpf, E, F; 26 hpf, G, H)—markers for erythropoiesis during primitive hematopoiesis. I–N2) Knockdown of adtrp1 expression reduced the expression level of pu-1 (12 hpf, I, J; 18 hpf, K, L; 24 hpf, M1–N2), a myeloid progenitor marker. O1–R2) Knockdown of adtrp1 expression reduced the expression levels of mpo (26 hpf; O1–P2), a granulocyte marker, and l-plastin (26 hpf; Q1–R2), a monocyte/macrophage cell marker.