Table 2.
Characteristics, laboratory values, and outcomes of cases (patients with ARDS) and matched controls (patients without ARDS) included in the propensity score matched analysis
| Cases (patients with ARDS) |
Controls (patients without ARDS) |
P-value | |
|---|---|---|---|
| Number | 38 | 38 | |
| Age | 57.0 (45.0–67.0) | 62.0 (50.0–72.0) | 0.53 |
| Female | 13 (34.2) | 13 (34.2) | 1.00 |
| Study site | 0.16 | ||
| Korea | 18 (46.2) | 10 (25.6) | |
| New York | 7 (17.9) | 10 (25.6) | |
| Boston | 14 (35.9) | 19 (48.7) | |
| APACHE IIa | 27.5 (24.0–33.0) | 26.0 (18.0–35.0) | 0.62 |
| Sepsisb | 16 (42.1) | 33 (86.8) | <0.001 |
| Septic shock | 7 (18.4) | 4 (10.5) | 0.33 |
| Pneumonia | 33 (86.8) | 33 (86.8) | 1.00 |
| Intubation | 34 (89.5) | 32 (84.2) | 0.55 |
| Procalcitonin, ng/mLc | 6.0 (2.1–36.4) | 0.8 (0.2–4.8) | 0.03 |
| Creatinine, mg/dLa | 0.8 (0.6–1.6) | 1.0(0.7–1.9) | 0.48 |
| Bilirubin, mg/dLa | 1.0 (0.6–3.0) | 3.1 (0.5–6.1) | 0.61 |
| pH in arterial blooda | 7.34 (7.28–7.45) | 7.40 (7.28–7.46) | 0.79 |
| PaO2, mmHga | 72.9 (62.8–98.3) | 87.7 (69.3–113.3) | 0.92 |
| PaCO2, mmHga | 36.9 (29.8–44.9) | 32.4 (26.0–40.9) | 0.82 |
| Lactate, mEq/L | 2.4 (1.5–3.5) | 2.0 (1.3–3.4) | 0.23 |
| Albumin, g/dL | 2.5 (2.1–3.0) | 2.9 (2.4–3.5) | 0.2 |
| SP-D, ng/mL | 20.8 (12.7–38.4) | 7.9 (4.1–17.0) | 0.001 |
| Length of ICU stay | 8.0 (5.0–15.0) | 4.0 (2.0–10.0) | 0.006 |
| ICU Mortality | 7 (18.4) | 6 (15.8) | 0.76 |
| In-hospital Mortality | 14 (35.9) | 10 (26.3) | 0.32 |
Abbreviations: ARDS acute respiratory distress syndrome, APACHE Acute Physiology and Chronic Health Evaluation, PaO 2 arterial oxygen tension, PaCO 2 arterial carbon dioxide tension, SP-D Surfactant protein D, ICU intensive care unit
Data are presented as median (interquartile range) or as number (%)
aAt admission to medical ICU
bIt does not include patients with septic shock
cData are available for 19 patients (12 patients with and 7 patients without ARDS)