Table 2.
Comparison of characteristics between benign and malignant pancreatic schwannomas
| Benign (n = 60) | Malignant (n = 8) | P | |
|---|---|---|---|
| Mean age (years) | 56.3 ± 14.4 (20–87) | 51.1 ± 17.7 (24–74) | 0.358 |
| Sex (male/female), (male %) | 9:11 (45%) | 3:5 (37.5%) | 1.000 |
| Mean size (cm) | 5.2 ± 4.0 (1–20) | 14.0 ± 10.3 (5–33) | 0.004 |
| Location | |||
| Uncinate | 9 (15%) | 0 (0%) | 0.228 |
| Head | 22 (37%) | 5 (71%) | |
| Head + body | 3 (5%) | 0 (0%) | |
| Body | 14 (23%) | 0 (0%) | |
| Body + tail | 6 (10%) | 2 (29%) | |
| Tail | 6 (10%) | 0 (0%) | |
| Nature of tumor on imaging | |||
| Solid | 17 (30%) | 2 (25%) | 0.845 |
| Cystic | 26 (46%) | 3 (37.5%) | |
| Solid + cystic | 13 (23%) | 2 (25%) | |
| Not specified | 4 (7.1%) | 1 (12.5%) | |
| Imaging characteristics | |||
| Well-defined margins | 45 (96%) | 2 (33%) | 0.009 |
| Presence of calcifications | 5 (9.4%) | 0 (0%) | 1.000 |
| Pancreatic duct/CBD dilation | 2 (9.1%) | 0 (0%) | 1.000 |
| Relation to nearby structures | |||
| No changes in nearby structures | 12 (52%) | 0 (0%) | < 0.001 |
| Compressed/displaced vessels | 9 (39%) | 0 (0%) | |
| Encasement of vessels | 2 (8.7%) | 3 (50%) | |
| Invasion of viscera | 0 (0%) | 3 (50%) | |
| Treatment | |||
| Pancreaticoduodenectomy | 13 (22%) | 3 (37.5%) | |
| Pylorus-preserving pancreaticoduodenectomy | 7 (10%) | 0 (0%) | |
| Central pancreatectomy | 2 (3.0%) | 0 (0%) | |
| Distal pancreatectomy +/− splenectomy | 13 (19%) | 1 (12.5%) | |
| Enucleation | 8 (12%) | 0 (0%) | |
| Surgical resection NOS | 13 (19%) | 2 (25%) | |
| Unresectable | 0 (0%) | 2 (25%) | |
| Refused | 3 (4.5%) | 0 (0%) | |
| Mean follow-up (months) | 19.4 ± 16.0 (3–65) | 16.3 ± 11.6 (4–28) | |
| Died of disease | 0 | 1 | |