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Bioassay of calcium ionophore-induced promote relaxation in the right and left atrium. The vasodilator activity of effluent from the right and left atrial appendage was blocked 85.1 ± 7.9% and 88.9±3.5%, respectively, by the presence of the L-NMMA (10-M) in rings contracted with PGF 2 (2x10 M). Results are reported as means±SEM. * indicate significant difference between with and without L-NMMA groups (P<0.001)[10].
