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. 2017 Nov 3;13(11):951. doi: 10.15252/msb.20177701

Figure 6. MERTK is a prognostic marker in CRC patients.

Figure 6

  1. Western blot visualising MERTK expression in two negative (RKO and CC07) and two positive control cell lines (CaCo‐2 and HT55).
  2. IHC staining of MERTK expression in RKO (negative control) and CaCo‐2 (positive control) cells.
  3. IHC staining of three representative TMAs from patients enrolled in the QUASAR 2 clinical trial and the corresponding quantification of the signal by pathologists. Arrowheads indicate tumour cells positive for MERTK.
  4. Kaplan–Meier plots showing worse overall, disease‐free and recurrence‐free survival of patients with high cytoplasmic/membranous expression of MERTK. P‐values indicate the significance of MERTK as a predictor based on the Wald statistic.