Table 1.
Samples used in this study. This study used samples from our previous analysis as the discovery set, and added a genotyped cohort as well as two published in silico sources as the replication sets.
| Data and Source populations | Ethnicity | Case | Control | Total | |
|---|---|---|---|---|---|
| Discovery (Sun et al. 2016) (2) | Korean | East Asian | 1,710 | 6,836 | 8,546 |
| Han Chinese | East Asian | 490 | 493 | 983 | |
| Malaysian Chinese | East Asian | 285 | 287 | 572 | |
| Japanese | East Asian | 891 | 3,384 | 4,275 | |
| Shanghai Han Chinese | East Asian | 501 | 622 | 1,123 | |
| Beijing Han Chinese | East Asian | 601 | 1,034 | 1,635 | |
| Replication (Genotyped) (Morris et al. 2016) (5) (Bentham et al. 2015) (4) | Hong-Kong | East Asian | 1,456 | 955 | 2,411 |
| Han Chinese (5) | East Asian | 1,659 | 3,398 | 5,057 | |
| European (4,5) | European | 4,063 | 6,959 | 11,022 | |
| Meta-analysis | Total | 11,656 | 23,968 | 35,624 | |