Table 2.
Biomarker | Healthy acclimatized controls, n = 50 | Altitude illness, n = 125 | P |
---|---|---|---|
ET-1 | 1.42 (1.09–1.81) | 1.76 (1.27–2.41) | 0.006 |
sE-Selectin | 18.42 (14.67–25.90) | 19.86 (13.82–24.93) | 0.492 |
Ang-2 | 0.53 (0.37–1.12) | 0.79 (0.48–1.25) | 0.063 |
Ang-1 | 11.95 (4.01–27.33) | 12.20 (5.71–24.57) | 0.887 |
sICAM-1 | 108.75 (95.68–132.30) | 111.80 (97.15–127.30) | 0.865 |
sTie2 | 16.48 (11.68–20.46) | 15.93 (12.39–18.55) | 0.490 |
sEng | 10.0 (8.7–12.2) | 9.15 (7.34–11.59) | 0.124 |
sKDR | 5.44 (4.42–6.69) | 4.69 (3.89–5.73) | 0.001 |
BDNF | 9.9 (2.9–18.7) | 8.38 (3.38–16.28) | 0.703 |
Angptl4 | 50.4 (40.6–68.4) | 65.94 (51.63–88.00) | 0.002 |
Resistin | 8.7 (6.4–13.8) | 12.43 (8.99–16.04) | <0.0001 |
sIL-1Ra | 0.28 (0.07–0.67) | 0.29 (0.10–0.86) | 0.417 |
Corin | 1.01 (0.63–1.25) | 0.73 (0.45–1.10) | 0.018 |
ACE | 91.6 (80.0–123.8) | 88.18 (64.89–109.35) | 0.036 |
Cystatin C | 832 (733–983) | 910.0 (792.0–1062.0) | 0.018 |
Renin | 0.28 (0.17–0.38) | 0.29 (0.19–0.43) | 0.666 |
BDNF, brain-derived neurotrophic factor. Data expressed as median (IQR), in ng/ml, analysed by Mann–Whitney U test.