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. 2016 Mar 16;23(3):taw005. doi: 10.1093/jtm/taw005

Table 2.

Biomarker levels in acclimatized controls and climbers who developed altitude illness

Biomarker Healthy acclimatized controls, n = 50 Altitude illness, n = 125 P
ET-1 1.42 (1.09–1.81) 1.76 (1.27–2.41) 0.006
sE-Selectin 18.42 (14.67–25.90) 19.86 (13.82–24.93) 0.492
Ang-2 0.53 (0.37–1.12) 0.79 (0.48–1.25) 0.063
Ang-1 11.95 (4.01–27.33) 12.20 (5.71–24.57) 0.887
sICAM-1 108.75 (95.68–132.30) 111.80 (97.15–127.30) 0.865
sTie2 16.48 (11.68–20.46) 15.93 (12.39–18.55) 0.490
sEng 10.0 (8.7–12.2) 9.15 (7.34–11.59) 0.124
sKDR 5.44 (4.42–6.69) 4.69 (3.89–5.73) 0.001
BDNF 9.9 (2.9–18.7) 8.38 (3.38–16.28) 0.703
Angptl4 50.4 (40.6–68.4) 65.94 (51.63–88.00) 0.002
Resistin 8.7 (6.4–13.8) 12.43 (8.99–16.04) <0.0001
sIL-1Ra 0.28 (0.07–0.67) 0.29 (0.10–0.86) 0.417
Corin 1.01 (0.63–1.25) 0.73 (0.45–1.10) 0.018
ACE 91.6 (80.0–123.8) 88.18 (64.89–109.35) 0.036
Cystatin C 832 (733–983) 910.0 (792.0–1062.0) 0.018
Renin 0.28 (0.17–0.38) 0.29 (0.19–0.43) 0.666

BDNF, brain-derived neurotrophic factor. Data expressed as median (IQR), in ng/ml, analysed by Mann–Whitney U test.