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. 2017 Apr 29;24(Suppl 1):S63–S80. doi: 10.1093/jtm/tax026

Table 2.

Acute diarrhea antibiotic treatment recommendations

Antibiotica Dose Treatment duration
Azithromycinc, d 1000 mg by mouth or Single or 1-day dividedb
500 mg by mouth 3 day course
Levofloxacin 500 mg by mouth Single doseb or 3 day course
Ciprofloxacin 750 mg by mouth or Single doseb
500 mg by mouth 3 day course
Ofloxacin 400 mg by mouth Single doseb or 3 day course
Rifaximine 200 mg by mouth three times daily 3 days
a

Antibiotic regimens may be combined with loperamide, 4 mg first dose, then 2 mg dose after each loose stool, not to exceed 16 mg in a 24 hour period.

b

If symptoms are not resolved after 24 hours, continue daily dosing for up to 3 days.

c

Use empirically as first line in Southeast Asia and India to cover fluoroquinolone resistant Campylobacter or in other geographical areas if Campylobacter or resistant ETEC are suspected.

d

Preferred regimen for dysentery or febrile diarrhea.

e

Do not use if clinical suspicion for Campylobacter, Salmonella, Shigella or other causes of invasive diarrhea.