Table 1.
Cell lines (XPA− vs. XPA+) | Genes Analyzed | FDR 0.05 (High + Low) | FC ≥ 1.5 (High + Low) |
---|---|---|---|
XP2OS vs. XPA/XP2OS | 14117 | 9526 | 1721 + 2206 |
XP12RO vs. XPA/XP12RO | 13669 | 10283 | 2750 + 2625 |
KO38 vs. HeLa S3 | 14564 | 9520 | 1769 + 1701 |
KO142 vs. HeLa S3 | 13824 | 8364 | 1642 + 1422 |
Common genes | 12022 | 176 + 149 | 11 + 16 |
The first column shows the number of genes analyzable by RNA-Seq for each XPA-proficient/deficient cell pair. The second column shows the number of genes with differential expression at a False Discovery Rate (FDR) of 0.05. The ratio of gene expression was calculated for XPA+/XPA− for each cell pair; positive log 2 values are termed “high” and negative log 2 values are termed “low”. The third column shows for each cell pair the number of “high” or “low” genes with fold change (FC) of 1.5 or more.