Table 1.
Baseline characteristics of patients with cutaneous lupus erythematosus and subjects without cutaneous lupus erythematosus
| Characteristic | Patients with CLE (n=155) | Subjects without CLE (n=155) | P-values |
|---|---|---|---|
| Demographics | |||
| Age, mean (s.d.), years | 48 (16) | 48 (16) | 0.96 |
| Sex, female, n (%) | 100 (65) | 100 (65) | 1.00 |
| Follow-up, median (interquartile range), years | 14.6 (8.1–23.6) | 15.8 (8.7–24.3) | – |
| Race, white (%)a | 117 (88.0) | 136 (98.6) | 0.03 |
| History of malignancy prior to index date | |||
| Any cancer, n (%) | 11/155 (7.1) | 14/155 (9.0) | 0.53 |
| Any cancer, n (%)b | 3/155 (1.9) | 5/155 (3.2) | 0.57 |
| Co-morbidities | |||
| Smoking, current, n (%)c | 61 (39.6) | 32/155 (20.6) | 0.001 |
| BMI, mean (s.d.), kg/m2d | 26.3 (7.1) | 26.5 (5.1) | 0.18 |
| Cardiovascular disease, n (%) | 17/155 (11.0) | 11/155 (7.1) | 0.23 |
| Hypertension, n (%)e | 85/155 (54.8) | 72 (46.8) | 0.16 |
| Diabetes mellitus, n (%)f | 24 (15.7) | 18 (12.2) | 0.38 |
| Hyperlipidaemia, n (%)g | 62/155 (40.0) | 72 (47.1) | 0.22 |
| Family history of early CAD, n (%)d | 6 (4.1) | 6 (3.9) | 0.95 |
aData available for only 133 patients with CLE and 138 subjects without CLE.
bAll skin cancers prior to index date were non-melanoma skin cancers; there were no cases of melanoma.
cData available for only 154 patients with CLE.
dData available for 147 patients with CLE and 144 non-CLE controls.
eData available for only 154 subjects without CLE.
fData available for only 153 patients with CLE and 148 subjects without CLE.
gData available for only 153 patients with CLE.
hData available for only 147 patients with CLE and 152 subjects without CLE.
CAD: coronary artery disease; CLE: cutaneous lupus erythematosus.