Table 1.
Renal markers, calcium and phosphate concentrations at presentation and follow-up of a hypercalcaemic 4-month-old female entire domestic shorthair cat (case 1)
| 5 days prior to referral | Day 0 | Day 7 | Day 8 | Day 9 | Day 10 | Day 11 | Day 12 | Day 13 | Day 14 | Day 17 | Day 31 | RI | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Urea (mmol/l) | 15.0 | – | 13.5 | – | – | – | – | – | – | 8.4 | – | – | 6.0–10.0 |
| Creatinine (μmol/l) | 137 | – | 88 | – | – | – | – | – | – | 44 | – | – | 60–170 |
| Total calcium (mmol/l) | 4.68 | – | 3.83 | – | – | – | – | – | – | 2.69 | – | 2.52 | 1.60–3.0 |
| Ionised calcium (mmol/l) | – | – | 2.02 | 1.87 | 1.79 | 1.85 | 1.92 | 1.56 | 1.43 | 1.33 | 1.32 | 1.30 | 1.10–1.40 |
| Phosphate (mmol/l) | 2.56 | – | 2.14 | – | – | – | 1.98 | – | – | 1.35 | 1.32 | 1.47 | 1.40–2.60 |
| Calcium × phosphate product (mmol2/l2) | 11.98 | – | 8.20 | – | – | – | – | – | – | 3.63 | – | 3.70 | <5.6 |
| Treatment | – | D | IVFT, D, F, Pr | IVFT, D, F, Pr, P | IVFT, D, F, Pr | D, F, Pr | Pr | – | – | ||||
RI = reference interval; D = doxycycline; IVFT = intravenous fluid therapy; F = furosemide; Pr = prednisolone; P = pamidronate