Hemagglutination-inhibition (HI) titers of children vaccinated with 2010–2011 trivalent inactivated influenza vaccine (TIV). HI titers to influenza virus strains included in the 2010–2011 TIV (2009 pandemic influenza A[H1N1] virus [A{H1N1}pdm09], A/Perth/16, and B/Bris/60), the 2009–2010 TIV (A/Bris/59, A/Bris10, and B/Bris/60), and the 2008–2009 TIV (B/Flor/4) were assessed at 0 days, 28 days, and 7 months after vaccination. Geometric mean titer (GMT) ratios (fold rise) were calculated using repeated measures linear mixed models for 28 days vs 0 days, 7 months vs 0 days, and 7 months vs 28 days. A GMT ratio of >1 (line) is indicative of a higher postvaccination response. Error bars represent 1 standard error. *P ≤ .05, **P ≤ .01, and †P ≤ .001.