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. Author manuscript; available in PMC: 2017 Dec 15.
Published in final edited form as: J Infect Dis. 2016 Aug 28;214(10):1477–1486. doi: 10.1093/infdis/jiw380

Figure 5.

Figure 5

Effect of prior vaccination on T-cell responses. The percentage of interferon γ–secreting CD4+CD69+ and TNF-α–secreting CD8+CD69+ cells responding to stimulation with live 2009 pandemic influenza A(H1N1) virus (A[H1N1]pdm09) or A/Perth/16 virus were determined in subjects vaccinated (V) with seasonal influenza vaccine or the monovalent A(H1N1)pdm09 vaccine during the 2009–2010 influenza season as compared to subjects who were not vaccinated (UV) with these respective vaccines. Differences between previously vaccinated and unvaccinated subjects were determined using unpaired t tests. Error bars represent 1 standard error. *P ≤ .05.