Table 3. Sensitivity to selected parameters of the incremental cost-effectiveness ratio (ICER) of replacing presumptive diagnosis by rapid diagnostic tests in drug shops in Mukono District, Uganda, 2011 (US$1 = UGX2523).

Parameter &	--- ICER in US$ ---		Parameter &	--- ICER in US$ ---
	Health sector	Societal		Health sector	Societal
Malaria prevalence among customers (43% and 32%)			Prob. of subs. treatment in mRDT arm (9.8%)
10%	-0.09	2.72	2%	0.55	3.34
20%	0.08	3.21	20%	0.55	4.47
40%	0.61	4.82	35%	0.55	5.40
60%	1.92	8.72	Prob. of subs. treatment in presumptive arm (10.2%)
80%	9.72	32.03	2%	0.55	4.20
Sensitivity of mRDT (92%)			20%	0.55	3.39
70%	0.28	4.61	35%	0.55	2.71
85%	0.48	4.04	ACT price
100%	0.63	3.61	30% decrease	1.02	4.30
Specificity of mRDT (63%)			40% decrease	1.18	4.46
50%	0.98	4.75	50% decrease	1.34	4.61
70%	0.37	3.44	mRDT price (US$0.70)
90%	0.00	2.63	30% decrease	-0.08	3.20
100%	-0.14	2.33	40% decrease	-0.29	2.99
Adherence to negative mRDT (99%)			50% decrease	-0.50	2.78
40%	2.49	7.61	Discount rate (3%)
60%	1.56	5.81	1%	0.56	3.84
80%	0.96	4.63	7%	0.54	3.82
Change in number of customers in mRDT arm			10%	0.53	3.81
40% lower	2.21	5.49	Com. sens., training and intense sup. (every 5 years)
40% higher	-0.16	3.12	Every 3 years	0.49	3.77
80% higher	-0.55	2.73	Every 7 years	0.58	3.86
100% higher	-0.69	2.59	Opportunity cost per day (US$1.2)
Change in number of customers in presumptive arm			US$0.4	0.55	3.26
40% lower	-1.23	2.05	US$0.8	0.55	3.54
40% higher	1.32	4.60	US$1.6	0.55	4.11
80% higher	1.74	5.02	US$2.0	0.55	4.39
100% higher	1.89	5.17	US$2.5	0.55	4.75

^& Actual parameter value observed in the trial [24] is shown in parenthesis.