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. 2017 Dec 15;12(12):e0189741. doi: 10.1371/journal.pone.0189741

Fig 3. Proteasome inhibitors affected ASFV replication in porcine macrophages.

Fig 3

(A) A cytotoxicity assay of inhibitors MG132 (1 μM), Lactacystin (20 μM) and Bortezomib (0.5 μM) was used to select the non-toxic working concentrations. (B) Quantitation of ASFV viral DNA at 16 hpi in macrophages pretreated 1 h with 1μM MG132, 20μM Lactacystin and 0.05μM Bortezomib. Data were compared to DMSO. Significant differences are marked with asterisks as indicated (*p<0.05; **p<0.01; ***p<0.001).