Table 4. The percentage of β-CD that was occupied by dexamethasone (β-CDIC) in the pHEMA/MMA/β-CD hydrogels and the percentage of dexamethasone that loaded via non-specific binding (PNC) out of the total loaded amount.
| Sample Code | β-CDIC (%) | PNC (%) | ||||
|---|---|---|---|---|---|---|
| 1Immersion condition I | 2Immersion condition II | 3Immersion condition III | Immersion condition I | Immersion condition II | Immersion condition III | |
| pHEMA/MMA | - | - | - | 100 (-) | 100 (-) | 100 (-) |
| pHEMA/MMA/β-CD1 | 1.47 (0.23) | 7.93 (0.14) | 8.86 (0.23) | 63.08 (1.36) | 68.41 (2.41) | 72.17 (0.23) |
| pHEMA/MMA/β-CD2 | 2.35 (0.12) | 8.30 (0.29) | 9.31 (0.17) | 34.74 (2.47) | 50.83 (1.38) | 55.26 (1.81) |
| pHEMA/MMA/β-CD3 | 2.89 (0.21) | 9.14 (0.16) | 10.03 (0.33) | 22.43 (0.64) | 38.50 (1.73) | 43.31 (2.52) |
| pHEMA/MMA/β-CD4 | 2.54 (0.14) | 7.50 (0.13) | 7.99 (0.24) | 19.81 (1.32) | 36.41 (0.85) | 41.84 (0.28) |
1 Immersion condition I included an immersion solution with a dexamethasone concentration of 0.04 mg ml-1 at 25°C;
2 Immersion condition II included an immersion solution with a dexamethasone concentration of 0.08 mg ml-1 at 25°C; and
3 Immersion condition III included an immersion solution with a dexamethasone concentration of 0.08 mg ml-1 at 37°C.