Table 3.
Time-specific pathways enriched among TSGs at all 5 time points. TSGs, time-specific genes at each time point; hpi, hours post-injection.
| Pathway | Pathway ID | FDR |
|---|---|---|
| 0 h (control) | ||
| Vasopressin-regulated water reabsorption | ko04962 | 1.08E-09 |
| Progesterone-mediated oocyte maturation | ko04914 | 1.96E-03 |
| Phospholipase D signaling pathway | ko04072 | 2.93E-03 |
| 6 hpi | ||
| Prion diseases | ko05020 | 1.571E-10 |
| Dorso-ventral axis formation | ko04320 | 1.174E-06 |
| Notch signaling pathway | ko04330 | 1.266E-06 |
| Thyroid hormone signaling pathway | ko04919 | 3.719E-05 |
| T cell receptor signaling pathway | ko04660 | 0.0007369 |
| Fc gamma R-mediated phagocytosis | ko04666 | 0.0060352 |
| ECM-receptor interaction | ko04512 | 0.0464513 |
| 12 hpi | ||
| Complement and coagulation cascades | ko04610 | 1.25E-02 |
| 24 hpi | ||
| DNA replication | ko03030 | 2.105E-15 |
| Cell cycle | ko04110 | 5.712E-08 |
| Mismatch repair | ko03430 | 0.0004709 |
| Pyrimidine metabolism | ko00240 | 0.0011964 |
| Homologous recombination | ko03440 | 0.0032069 |
| Oocyte meiosis | ko04114 | 0.0057862 |
| Nucleotide excision repair | ko03420 | 0.0114305 |
| Systemic lupus erythematosus | ko05322 | 0.049154 |
| 48 hpi | ||
| Olfactory transduction | ko04740 | 0.0037022 |
| Glycosaminoglycan degradation | ko00531 | 0.004054 |
| Thyroid hormone synthesis | ko04918 | 0.0116272 |