Skip to main content
. 2017 May 23;8(60):101026–101041. doi: 10.18632/oncotarget.18197

Figure 5. Let-7g increases ABCA1 expression by suppressing miR-33a.

Figure 5

(A) 2 putative RelA/p50-binding sites in the SREBF2 promoter. Macrophages infected with LV-let7g-sponge or LV-let7g were used for the ChIP assay by using RelA/p50 antibodies or an irrelevant antibody (Ig, nonimmune IgG). M: molecular weight marker (100 bp ladders). (B) Western blot analysis of ABCA1 protein in macrophages. (C) SREBF2 mRNA and miR-33a levels in macrophages. Data are presented as mean ± SEM from 3 independent experiments. *P < 0.05; **P < 0.01; ***P < 0.001.