Table 1. Association between clinicopathological characteristics and KHSRP expression.
| Clinicopathological factors | n | KHSRP immunoreactivity (Cytoplasm) | P valuea | KHSRP immunoreactivity (Nucleus) | P valuea | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| High (%) | Low (%) | High (%) | Low (%) | |||||||||
| Total | 104 | 59 | (56.7) | 45 | (43.3) | 68 | (65.4) | 36 | (34.6) | |||
| Gender | ||||||||||||
| Male | 85 | 46 | (54.1) | 39 | (45.9) | 0.3116 | 54 | (63.5) | 31 | (36.5) | 0.5944 | |
| Female | 19 | 13 | (68.4) | 6 | (31.6) | 14 | (73.7) | 5 | (26.3) | |||
| Age | ||||||||||||
| Mean ± SD (yr) | 64.1 ± 8.4 | 63.2 | ± 7.6 | 65.3 | ± 9.3 | 0.2031 | 64.1 | ± 8.1 | 64.1 | ± 9.1 | 0.9758 | |
| Histopathological grading | ||||||||||||
| Well and moderately differentiated | 75 | 43 | (57.3) | 32 | (42.7) | 1.0000 | 44 | (58.7) | 31 | (41.3) | 0.0227 | |
| Poorly differentiated | 29 | 16 | (55.2) | 13 | (44.8) | 24 | (82.8) | 5 | (17.2) | |||
| Lymphatic invasion (ly) | ||||||||||||
| Negative | 45 | 23 | (51.1) | 22 | (48.9) | 0.3263 | 31 | (68.9) | 14 | (31.1) | 0.5397 | |
| Positive | 59 | 36 | (61.0) | 23 | (39.0) | 37 | (62.7) | 22 | (37.3) | |||
| Venous invasion (v) | ||||||||||||
| Negative | 73 | 37 | (50.7) | 36 | (49.3) | 0.0828 | 44 | (60.3) | 29 | (39.7) | 0.1166 | |
| Positive | 31 | 22 | (71.0) | 9 | (29.0) | 24 | (77.4) | 7 | (22.6) | |||
| Depth of tumor invasion (pT) | ||||||||||||
| pT1 | 56 | 27 | (48.2) | 29 | (51.8) | 0.0747 | 32 | (57.1) | 24 | (42.9) | 0.0654 | |
| pT2-4 | 48 | 32 | (66.7) | 16 | (33.3) | 36 | (75.0) | 12 | (25.0) | |||
| N stage (pN) | ||||||||||||
| pN0 | 55 | 32 | (58.2) | 23 | (41.8) | 0.8435 | 35 | (63.6) | 20 | (36.4) | 0.8367 | |
| pN1-3 | 49 | 27 | (55.1) | 22 | (44.9) | 33 | (67.3) | 16 | (32.7) | |||
| pStage | ||||||||||||
| pI | 43 | 23 | (53.5) | 20 | (46.5) | 0.6882 | 24 | (55.8) | 19 | (44.2) | 0.0976 | |
| pII-VI | 61 | 36 | (59.0) | 25 | (41.0) | 44 | (72.1) | 17 | (27.9) | |||
Statistically significant values are in boldface type.
aP values are from χ2 or Fisher's exact test and were statistically significant at < 0.05.