Table 2. Clinicopathological characteristics of patients with the MF-type and PI-type of intrahepatic cholangiocarcinoma.
| Characteristic | MF-type (n = 2480) | PI-type (n = 199) | Total (n = 2679) | Pa |
|---|---|---|---|---|
| No (%) | No (%) | No (%) | ||
| Age (years) | 0.878 | |||
| ≤ 60 | 753 (30.4) | 62 (31.2) | 815 (30.4) | |
| > 60 | 1727 (69.6) | 137 (68.8) | 1864 (69.6) | |
| Race | 0.005 | |||
| White | 1942 (78.3) | 149 (74.9) | 2091 (78.1) | |
| Black | 190 (7.7) | 28 (14.1) | 218 (8.1) | |
| Otherb | 348 (14.0) | 22 (11.0) | 370 (13.8) | |
| Sex | 0.878 | |||
| Male | 1425 (57.5) | 116 (58.3) | 1541 (57.5) | |
| Female | 1055 (42.5) | 83 (41.7) | 1138 (42.5) | |
| Marital status | 0.350 | |||
| Married | 1442 (58.1) | 123 (61.8) | 1565 (58.4) | |
| Not marriedc | 1038 (41.9) | 76 (38.2) | 1114 (41.6) | |
| Histologic grade | 0.152 | |||
| Grade I | 123 (5.0) | 4 (2.0) | 127 (4.7) | |
| Grade II | 517 (20.8) | 52 (26.1) | 569 (21.2) | |
| Grade III | 463 (18.7) | 38 (19.1) | 501 (18.7) | |
| Grade IV | 9 (0.4) | 1 (0.5) | 10 (0.5) | |
| Unknown | 1368 (55.1) | 104 (52.3) | 1472 (54.9) | |
| AJCC stage (8th edition, 2017) | 0.043 | |||
| Stage I | 597 (24.1) | 48 (24.1) | 645 (24.1) | |
| Stage II | 533 (21.5) | 28 (14.1) | 561 (20.9) | |
| Stage III | 498 (20.1) | 40 (20.1) | 538 (20.1) | |
| Stage IV | 852 (34.3) | 83 (41.7) | 935 (34.9) | |
| Node stage | 0.979 | |||
| N0 | 1677 (67.6) | 133 (66.8) | 1810 (67.6) | |
| N1 | 706 (28.5) | 57 (28.7) | 763 (28.5) | |
| NX | 97 (3.9) | 9 (4.5) | 106 (3.9) | |
| Surgery performed | 0.029 | |||
| Yes | 652 (26.3) | 67 (33.7) | 719 (26.8) | |
| No | 1828 (73.7) | 132 (66.3) | 1960 (73.2) |
Abbreviations: AJCC, American Joint Committee on Cancer. MF, mass-forming; PI, periductal infiltrating; NX: Regional lymph nodes could not be assessed.
aBold type indicates statistical significance.
bOther includes Asian/Pacific Islander and American Indian/Alaskan native.
cNot married includes single, divorced, separated, unmarried or domestic partner, and widowed.