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. 2017 Sep 8;8(60):101406–101417. doi: 10.18632/oncotarget.20738

Figure 5. Suppressing Xist inhibits tumorigenicity and proliferation in vivo.

Figure 5

(A) Photograph of tumors harvested from LV-NC and LV-siXist 1# cells in nude mice. (B) The tumor volumes kinetics of tumors in nude mice. Tumor diameters were measured every week. (C) The tumor weights were lower in LV-siXist 1# group than that in the control group. (D) The tumor sections underwent IHC staining using antibodies against Ki-67. Data are represented as mean±SD of three independent experiments. **P < 0.01 compared with control group. (E) The tumor sections underwent TUNEL staining using TUNEL apoptosis detection kit.