Table 2. Molecular function analysis of the genetic interaction network associated with liver-aggressive explant in terms of Gene Ontology (GO).
GO ID | Molecular Function | Observed Gene Count | FDR |
---|---|---|---|
GO.0004702 | receptor signaling protein serine/threonine kinase activity | 15 | 3.13E-21 |
GO.0005515 | protein binding | 7 | 2.03E-05 |
GO.0004708 | MAP kinase kinase activity | 41 | 2.41E-05 |
GO.0017137 | Rab GTPase binding | 5 | 2.74E-05 |
GO.0031489 | myosin V binding | 6 | 0.000307 |
GO.0017022 | myosin binding | 4 | 0.000381 |
GO.0004709 | MAP kinase kinase kinase activity | 5 | 0.000518 |
GO.0005488 | binding | 4 | 0.00169 |
GO.0017075 | syntaxin-1 binding | 59 | 0.00354 |
GO.0004707 | MAP kinase activity | 3 | 0.00402 |
GO.0004674 | protein serine/threonine kinase activity | 3 | 0.00636 |
GO.0004946 | bombesin receptor activity | 9 | 0.0113 |
GO.0005102 | receptor binding | 2 | 0.0128 |
GO.0004908 | interleukin-1 receptor activity | 14 | 0.018 |
GO.0019905 | syntaxin binding | 2 | 0.0215 |
GO.0019899 | enzyme binding | 4 | 0.0253 |
GO.0004871 | signal transducer activity | 15 | 0.032 |
GO.0005179 | hormone activity | 16 | 0.0377 |
GO.0060089 | molecular transducer activity | 4 | 0.0377 |
GO.0086083 | cell adhesive protein binding involved in bundle of Hiscell-Purkinje myocyte communication | 17 | 0.0377 |
Abbreviations: FDR, false discovery rate; GO, Gene Ontology.