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. 2017 Sep 12;8(60):101452–101460. doi: 10.18632/oncotarget.20843

Table 2. Molecular function analysis of the genetic interaction network associated with liver-aggressive explant in terms of Gene Ontology (GO).

GO ID Molecular Function Observed Gene Count FDR
GO.0004702 receptor signaling protein serine/threonine kinase activity 15 3.13E-21
GO.0005515 protein binding 7 2.03E-05
GO.0004708 MAP kinase kinase activity 41 2.41E-05
GO.0017137 Rab GTPase binding 5 2.74E-05
GO.0031489 myosin V binding 6 0.000307
GO.0017022 myosin binding 4 0.000381
GO.0004709 MAP kinase kinase kinase activity 5 0.000518
GO.0005488 binding 4 0.00169
GO.0017075 syntaxin-1 binding 59 0.00354
GO.0004707 MAP kinase activity 3 0.00402
GO.0004674 protein serine/threonine kinase activity 3 0.00636
GO.0004946 bombesin receptor activity 9 0.0113
GO.0005102 receptor binding 2 0.0128
GO.0004908 interleukin-1 receptor activity 14 0.018
GO.0019905 syntaxin binding 2 0.0215
GO.0019899 enzyme binding 4 0.0253
GO.0004871 signal transducer activity 15 0.032
GO.0005179 hormone activity 16 0.0377
GO.0060089 molecular transducer activity 4 0.0377
GO.0086083 cell adhesive protein binding involved in bundle of Hiscell-Purkinje myocyte communication 17 0.0377

Abbreviations: FDR, false discovery rate; GO, Gene Ontology.