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. 2017 Sep 12;8(60):101452–101460. doi: 10.18632/oncotarget.20843

Table 3. Biological process analysis of the genetic interaction network associated with liver-aggressive explant in terms of Gene Ontology (GO).

GO ID Biological Process Observed Gene Count FDR
GO.0051046 regulation of secretion 21 5.45E-10
GO.0080134 regulation of response to stress 28 6.97E-10
GO.1903530 regulation of secretion by cell 19 4.53E-09
GO.0051047 positive regulation of secretion 15 8.72E-09
GO.0032101 regulation of response to external stimulus 20 1.24E-07
GO.0032879 regulation of localization 31 1.24E-07
GO.0051049 regulation of transport 27 1.24E-07
GO.0051050 positive regulation of transport 20 1.24E-07
GO.0031347 regulation of defense response 18 3.95E-07
GO.0010647 positive regulation of cell communication 25 4.18E-07
GO.0060341 regulation of cellular localization 22 4.18E-07
GO.0043410 positive regulation of MAPK cascade 14 8.81E-07
GO.0014047 glutamate secretion 6 1.17E-06
GO.0050690 regulation of defense response to virus by virus 6 1.38E-06
GO.0023056 positive regulation of signaling 23 1.79E-06
GO.0051650 establishment of vesicle localization 10 2.00E-06
GO.0046717 acid secretion 7 3.36E-06
GO.0001934 positive regulation of protein phosphorylation 17 5.02E-06
GO.0016079 synaptic vesicle exocytosis 37 3.10E-13
GO.0045860 positive regulation of protein kinase activity 11 3.55E-13

Abbreviations: FDR, false discovery rate; GO, Gene Ontology; MAPK: mitogen-actived protein kinase.