Table 1. Association of RNF187 expression with clinicopathological parameters of HCC patients.

ClinicopathologicalParameters	Total	RNF187 Expression		p value
		Negative	Positive
	209	115	94
Sex
Male	179	94	85	0.055
Female	30	21	9
Age range,yr				0.403
≤ 50	93	48	45
> 50	116	67	49
Tumor numbler				0.026
1	166	98	68
≥ 2	43	17	26
Tumor size, cm				1.90E-13
≤ 5	122	93	29
> 5	87	22	65
TNM stage				7.64E-11
I–II	144	101	43
III–IV	65	14	51
Grade of differentiation				0.065
I-II	152	89	63
III-IV	57	26	31
Microvascular/ bile duct invasion				0.003
Positive	59	23	36
Negative	150	92	58
HBX				0.491
Positive	167	94	73
Negative	42	21	21
Cirrhosis				0.855
Positive	187	104	83
Negative	22	11	11
AFP				1.000
≤ 400	131	72	59
> 400	78	43	35
ALT,U/L				0.684
≤ 75	181	101	8580
> 75	28	14	14

Abbreviations and Note: HCC, hepatocellular carcinoma; AFP, alpha-fetoprotein;TNM, tumor node metastasis; HBsAg, hepatitis B surface antigen; ALT, alanine aminotransferase; NS, not significant; The X² test was used for comparison between groups. 50% for RNF187.